Medications can be used in the context of Polycystic Ovary Syndrome (PCOS) when weight-management is part of the care plan. The options should be considered along with lifestyle and tailored to the individual. For example, insulin-sensitising oral treatments may be used in people with PCOS who have high metabolic risk. “Anti-obesity drugs” (such as GLP-1 agonists) may be considered in addition to diet and exercise. It’s important to emphasise that the first-line approach is lifestyle (diet, exercise, behavioural support), and medications are an additional options, dependent on each person’s symptoms, weight status, fertility goals and overall health.