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You should rotate your injection sites when using any weight loss medication injection. Repeatedly injecting in the same spot can cause irritation, bruising, lumps, or scarring under the skin, and may also affect how well the medicine is absorbed. Most weight loss injections are given subcutaneously (under the skin) — usually in the abdomen, thigh, or upper arm. To prevent skin problems and ensure consistent absorption, it’s best to inject in a different spot each time within the same area (for example, move 2–3 cm away from the last injection site).
Your doctor, nurse, or pharmacist can show you the correct technique and help plan a safe rotation schedule.